我院近5年来泌尿道感染病原菌及耐药性分析

The study on pathogenic bacteria status and bacterial drug-resistance of urinary tract infections in recent five years

目的了解泌尿道感染的常见病原菌及产超广谱β-内酰胺酶(ESBLs)情况,比较临床常见泌尿道病原菌对呋喃妥因与其它3种抗菌药物的耐药性的5年变化。方法使用ATBExpression全自动鉴定及药敏测试仪对细菌进行鉴定及耐药性分析,ESBLs的检测按NCCLS推荐的初筛、表型确认试验法操作。结果泌尿道感染的常见病原菌埃希菌属所占比例最高(5年平均56.7%),其次是假丝酵母菌(11.2%)。其中大肠埃希菌、肺炎克雷伯菌和变形杆菌产ESBLs检出率为30%。结论我院泌尿道感染的常见病原菌产ESBLs的比率较高,呋喃妥因对泌尿道感染病原菌耐药率较低。

Objective To investigate the common pathogenic bacteria and their status of producing extended-spectrum β-1actamases （ESBLs）, and compare their drag-resistance of pathogenic bacteria from urinary tract infections on Furadantin and the other three antimicrobial agents against in recent five years. Methods The bacteria were characterized by ATB expression automatic analytic system, their drugresistances were analysed with drag sensitivity detector;the suspiciously produced ESBLs was detected by standard screen test （recommended by NCCLS）. Results There were 56.7% Escheriehia and 11.2% Candida in pathogenic bacteria from urinary tract infections. The average detected rate of producing ESBLs E.coli, K. pneumoniae and Proteus were 30%.Conclusion There are higher detected rate in producing ESBLs bacteria among pathogenic bacteria from urinary tract infections.The drug resistant rate on Furadantin was lower in recent five years.