摘要
对哮喘模型大鼠气管的无载荷状态和零应力状态进行分析。与正常组相比,模型大鼠气管软骨剪开的张开角及所对应的残余应变绝对值均较正常组显著增大(P<0.05),而且随着x/L的增大而呈明显上升趋势。模型大鼠气管肌肉剪开的张开角及所对应的残余应变绝对值无显著变化,且沿气管轴向变化不明显。结果表明哮喘大鼠气管为了适应外在应力环境的变化,肌肉部分不断进行代偿性生长,导致哮喘大鼠气道重建。
In this study,the no-load state and zero-stress state of the asthma rat trachea were anlayazed. It was found that the opening angle and residual strains of the asthma rat trachea cut at the cartilaginous region was significantly larger than those of the normal rat. Compared with the coutrol rat, it was indicated that the opening angles and residual strains expressed by cutting at the muscular portion were basically identical along longitudinal location and those expressed by cutting at the cartilaginous region increased in the longitudinal direction in the asthma rta. The results shows that the muscle of trachea gradually growed because of changes of the mechanical environment, resulting in remodeling of the asthma rat trachea.
出处
《中国生物医学工程学报》
CAS
CSCD
北大核心
2006年第1期88-91,共4页
Chinese Journal of Biomedical Engineering
基金
国家自然科学基金资助项目(19972042)
