Is colonoscopy sufficient for colorectal cancer surveillance in all HNPCC patients?

A 34-year-old male with hereditary non-polyposis colon cancer with a mutation in hMSH2 line is reported. Despite regular colonoscopic follow-up, he developed cecal cancer involving the extraluminal area. Due to sub-occlusive symptoms, the patient was submitted to further colonoscopy, however with no clear evidence of neoplasia. Thin slice multiplanar reconstruction computed tomography CT scan performed thereafter revealed a transmural mass 2.5 cm in size localized near the cecal valve. Discussion is made on the reliability of colonoscopic examinations as well as the need for further investigations in the follow-up of patients at very high risk of right-sided colon cancer, such as male hMSH2 carrier affected by hereditary non-polyposis colon cancer.

有有在 hMSH2 的一个变化的结肠癌衬里的世袭 non-polyposis 的 34 岁的男性被报导。尽管有常规 colonoscopic 后续，他得了包含额外的钠区域的盲肠的癌症。由于亚 occlusive 症状，病人被提交推进结肠镜检查，然而没有瘤形成的清楚的证据。计算断层摄影术 CT 扫描此后执行了的多平面的重建揭示了的薄片透壁集中在在盲肠的阀门附近局部性的尺寸的 2.5 厘米。讨论在右边的结肠癌的很高的风险在病人的后续象对进一步的调查的需要一样在 colonoscopic 考试的可靠性上被做，例如世袭 non-polyposis 结肠癌影响的男 hMSH2 搬运人。