心包内全肺及部分左心房切除治疗Ⅲ期肺癌53例

Pneumonectomy via intrapericardial vascular management or combined with partial resection of left atrium in treatment of stage Ⅲ lung cancer: a report of 53 cases

为了探讨心包内全肺及部分左心房切除治疗Ⅲ期肺癌的疗效和价值,1988年2月～2001年12月对53例Ⅲ期肺癌行心包内全肺切除32例,合并部分左心房切除治疗17例,剖胸探查或单纯心包开窗4例。手术并发症发生率为17.0%(9/53),死亡2例(3.8%),随访率为96.1%,术后1、3和5年生存率分别为73.6%(39/53)、34.0%(18/53)和20.8%(11/53),其中2例生存超过7年。初步研究结果提示,Ⅲ期肺癌采用扩大切除能提高根治性手术切除率,延长患者生存期,改善生活质量,在临床上有应用价值。

The objective of this paper was to study the significance of pneumoneetomy via intraperieardial vascular management or combined with partial resection of left atrium in the treatment of stage Ⅲ lung cancer. From Feb ruary, 1988 to December, 2001, 32 patients with stage Ⅲ lung cancer underwent pneumoneetomy via intrapericardlal vascular management, and 17 cases underwent pueumonectomy combined with partial resection of left atrium. The incidence of postoperative complications was 17.0 % （9/53）. Two patients died and the mortality rate was 3. 8 %. The postoperative follow-up rate was 96.1%. The 1-, 3-, 5-year survival rates were 73.6% （39/53）,34. 0% （18/53）, 20. 8%（11/53）, respectively. Two patients have survived for 7 years. In conclusion, pneumoneetomy via intraperi eardial vascular management or combined with partial resection of left atrium in the treatment of stage Ⅲ lung cancer can enhance the possibility of radical resection, remarkably increase the long-term survival and improve the life quality of the patients. Therefore, it is clinically valuable.