摘要
深入了解性激素在“高红症”发病中的作用和位置,对海拔3700m地区即玉树结古42铭17~24岁健康青年,血清T、E2、FSH、LH、Hydrocortisone用RIA作了检测。选择海拔2260m西宁地区80例17~24岁健康青年作对照组。测定数据两地男女分别对照作出P值。结果提示,玉树青年的性激素和皮质醇血清浓度明显高于西宁地区青年。如T(μg/L):玉树青年男:112.66±67.12,西宁青年男:64.67±54.87(P<0.01),玉树女:12.29±5.62,西宁女:8.40±2.56(P<0.01)。T能增加EP的生成,还能直接促进骨髓制造红细胞,还与PGE有协同作用。说明在高原(山)缺氧环境,机体内首先发生变化在“高红症”发病中起主要作用是T、EP是继发的。
o study the effects of high altitude on sex hormone and cortisol of youngs.The serum speci-mens from 42 healthy youngs ,Mage 17~24 years,residing at 3 700m Yushu altitude were assayedfor the concentrations of T,E2,FSH,LH,PRL and cortisol using RIA,The results were comparedwith control group consisted of 80 youngs in Xining area of 2 260m.The results showed that theconcentration of sex hormone and cortisol of 3 700m yotings were significantly higher than thoseof Xining(P<0.05~0.01),The above findings suggested that the sex hormone and cortisol mayplay a role in the adaptation ofhumanbody to hypoxia and in the pathogenesis of high altitudedisease.
出处
《高原医学杂志》
CAS
1996年第2期29-31,共3页
Journal of High Altitude Medicine
关键词
性激素
高山病
Sex hormone
Cortisol
High altitude