离子交换树脂在药剂学中的应用进展

Advances of ion exchange resin in Pharmaceuticals

离子交换树脂药物载体在给药系统中的应用由于具有很多优点而得到了人们的重视。目前在控释、透皮给药、定位给药、速溶、离子导入透皮、鼻腔、局部给药和掩盖药物苦味等方面都有很深入的研究,在缓控释给药中占有特殊的地位。综述了这一药物载体在给药系统和作用部位应用的新进展,并对其应用前景进行了展望。

Ion exchange resin has demonstrated impressing advantages as a promising carrier in the drug delivery system, such as controlled release, transdermal, site-specific, fast dissolving, iontophoretically assisted transdermal, nasal, topical, and taste-masked systems. The targeted sustained-released drug delivery of the ion exchange resin was the most impressive in all of the available systems. This review presented the latest applications of the ion exchange resin as a drug carrier and addressed the trends of the ion exchange resin in the drug delivery system.