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同型半胱氨酸与抑郁 被引量：9

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摘要 本文就同型半胱氨酸(homocysteine,Hcy)与抑郁的关系、抑郁相关因素对血浆Hcy水平影响及Hcy在抑郁与心血管疾病伴发中的可能作用进行了综述。
作者 刘卫 钱令嘉
机构地区 军事医学科学院卫生环境医学研究所
出处 《国际精神病学杂志》 2006年第1期45-47,共3页 Journal Of International Psychiatry
关键词 高同型半胱氨酸(Hcy) 抑郁 心血管疾病
分类号 R749.4-1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献15

  • 1Joynt KE, Whellan DJ, 0 ' Connor CM,. et al: Depression and cardiovascular disease: mechanisms of interaction. Biological Psychiatry, 2003; 54: 238-261.
  • 2Bottiglieri T, Laundy M, Crelin R, et al: Homocysteine, folate, methylation, and monoamine metabolism in depression.Journal of Neurology Neurosurgery and Psychiatry, 2000; 69:228-232.
  • 3Sachdev PS, Parslow RA, Lux O, et al: Relationship of homocysteine, folic acid and vitamin B12 with depression in a middle-aged community sample. Psychol Med. 2005; 35(4) : 529-538.
  • 4Tolmunen T, Hintikka J, Voutilainen S, et al: Association between depressive symptoms and serum concentrations of homocysteine in men: a population study. Am J Clin Nutr. 2004;80 (6): 1574-1578.
  • 5Bjelland I, Tell GS, Vollset SE, et al: Folate, vitamin B12,homocysteine, and the MTHFR 677C-> T polymorphism in anxiety and depression: the Hordal and Homocysteine Study.Archives of General Psychiatry, 2003; 60 (6): 618-626.
  • 6Setnik B, de Souza FG, d' Almeida V, et al: Increased homocysteine levels associated with sex and stress in the learned helplessness model of depression. Pharmacdogy Biochemistry and Behavior, 2004; 77 (1): 155-161.
  • 7Gamaro GD, streck EI, Matte C, et al: Reduction of hippocampal Na^+ - K^+ -ATPase activity in rats subjected to and experimental model of depression. Neurochemical Research,2003; 28 (9): 1339-1344.
  • 8Streck EL, Zugno AI, Tagliari B, et al: On the mechanism of the inhibition of Na^+ - K^+ - ATPase activity caused by homocysteine. International journal of Developmental Neuroscience,2002, 20: 77-81.
  • 9Hoinkes A, Fleischer W: Implications for hyperhomocysteinemia: not homocysteine but its oxidized forms strongly inhibit neuronal network activity. Jorunal of the Neurological Sciences, 2004; 218: 109-114.
  • 10Morris MS, Fava M, Jacques PF, et al: Depression and folate status in the US Population. Psychotherepy Psychosomatics, 2003; 72 (2): 80-87.

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共引文献17

同被引文献148

引证文献9

二级引证文献83

国际精神病学杂志
2006年 第1期

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