急性淋巴细胞白血病的免疫分型及临床和预后

THE IMMUNOPHENOTYPES OF ACUTE LYMPHOBLASTIC LEUKAEMIA AND THEIR CLINIC PROGNOSIS

35例ALL病人的免疫表型及临床和预后。35例分为C—ALL、T—ALL、N—ALL、C/T—ALL和杂合白血病(HAL)五种类型。C—ALL和N—ALL预后较好,T—ALL,HAL预后差且易伴有高WBC数和白血病浸润体征。C—ALL包括B_1^+和B_1两型,T—ALL分为胸腺三期,N—ALL包括三种不同情况,作者认为ALL的9期分类法较5型分类更为合理,并建议重视WT_1B_4和粒系抗原的意义并注意将免疫分型与临床疗效相结合。

The phenotypes clinical features and prognoses of 35 cases all wereanalysed. The results showed that all can be divided into five groups: CALL, T-ALL, N--ALL, C/ T-ALL and hybrid acute leukaemia (HAL). The C-ALL and N-ALL had better prognosis and lower WBC count then T-ALL, and HAL,. The C-ALL included two type: B1 or B1+; T-ALL included three in trathymic stages, N-ALL can be divided into three different origh of cells. The authors Suggested it is more suitable to divide ALL into T-ALL (three stages) and Non-T-ALL (six groups).