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老年急性冠脉综合征与血小板P-选择素表达率的相关性研究 被引量:3

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摘要 目的探讨血小板P-选择素表达率在老年急性冠脉综合征(ACS)患者中的变化以及血小板P-选择素与冠状动脉狭窄程度的相关性。方法应用流式细胞仪对经冠状动脉造影确诊的51例老年ACS患者、33例稳定型心绞痛(SAP)患者和34例老年正常对照者的血小板P-选择素表达率进行检测,分析血小板P-选择素表达率与老年冠心病的稳定性、狭窄程度的关系。结果老年急性冠脉综合征患者P-选择素的表达率明显高于对照组和稳定性心绞痛组(P<0.05),而SAP组和对照组无统计学差异。老年冠心病患者冠脉狭窄程度Gensini评分与血小板膜P-选择素表达率之间无很好的相关性(P>0.05)。结论P-选择素参与炎症反应和血栓形成,血小板P-选择素表达率可作为老年冠心病患者动脉粥样硬化斑块稳定性的判定指标。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2006年第1期5-6,共2页 Chinese Journal of Gerontology
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参考文献8

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