汽化电切加黏膜下定期浸润注射吡柔比星预防膀胱癌复发(附56例报告)

The Prevention of Recurrence of Bladder Tumor by Transurethral Electro_Vaporization Combined with Bladder Submucous Layer Injection of Pirarubicin(Report of 56 Cases)

目的探讨汽化电切膀胱肿瘤术后行肿瘤周围黏膜下定期浸润注射吡柔比星（THP）预防膀胱癌复发的效果。方法回顾分析56例膀胱肿瘤。经尿道汽化电切肿瘤术后行肿瘤周围黏膜下定期浸润注射THP患者的临床资料。结果56例中51例获随访。随访时间3。5年。平均3年10个月。术后1年复发率5．88％（3／51），2年复发率11．76％（6／51），3年复发率19．61％（8／51）。结论膀胱肿瘤汽化电切术后行黏膜下定期浸润注射THP，方法简单。预防膀胱癌术后复发安全有效。

Objective To investigate the effect of transurethral electro-vaporization combined with submucous membrane regular injection of Pirarubiein （THP） to control the recurrence of bladder tumor. Methods Clinical data of 56 patients with bladder tumor were reviewed. The tumor was ablated by transurethral electro-vaporization, and then THP was regularly injected into submueous membrane around tumor. Results 51 samples from the total 56 were visited more than 3 years in followed up 3 - 5 years. The rate of recurrence was respectively 5.88 % （3/51 ）, 11.76 % （6/51 ） and 19.61 % （8/51） at the 1st year, 2nd year, 3rd year. Conclusions Transurethral electro-vaporization combined with submucous membrane regular injection of THP for controlling postoperative recurrence of bladder tumor was effective, and its characteristics were simple and less complication.