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阿尔茨海默病转基因小鼠的研究现状与展望 被引量:4

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出处 《中国行为医学科学》 CSCD 2006年第2期190-192,共3页 Chinese Journal of Behavioral Medical Science
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参考文献22

  • 1Lalonde R,Dumont M,Staufenbiel M,et al.Spatial learning,exploration,anxiety,and motor coordination in female APP23 transgenic mice with the Swedish mutation.Brain Research,2002,956:36-44.
  • 2Joanne BS,Donna LM,Jill AA,et al.Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein.Molecular Brain Research,1999,66:150-162.
  • 3Jurgen Gotz.Tau and transgenic animal models.Brain Research Reviews,2001,35:266-286.
  • 4Janus C,Amelio SD,Amitay O,et al.Spatial learning in transgenic mice expressing human presenilin1 (PS1) transgenes.Neurobiology of aging,2000,21:541-549.
  • 5Fagan AM,Watson M,Parsadanian M,et al.Human and murine ApoE markedly alters A3 metabolism before and after plaque formation in a mouse model of Alzheimer's disease.Neurobiology of Disease ,2002,9:305-318.
  • 6Delacourte A,Sergeant N,Champain D,et al.Nonnoverlapping but synergetic tau and APP pathologies in sporadic Alzheimer's disease.Neurology,2002,59:398-407.
  • 7刘薇,卢光秀.阿尔茨海默病相关PDAP_(SW)转基因小鼠模型的表型研究[J].中华神经科杂志,2002,35(4):201-203. 被引量:2
  • 8Claudia S,Masato H,Patrick L,et al.Transgenic mice overexpressing amyloid beta protein are an incomplete model of Alzheimer disease.Experimental Neurology,2004,188:52 -64.
  • 9Fred van L.Single and multiple transgenic mice as models for Alzheimer's disease.Progress in Neurobiology,2000,61:305-312.
  • 10Jurgen G,Andreas S,Fred H,et al.Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease:insight from transgenic mouse and tissue-culture models.International Journal of Developmental Neuroscience ,2004,22:453-465.

二级参考文献20

  • 1鄢盛恺,周新,哈黛文.聚合酶链反应限制性片段长度多态性检测载脂蛋白E基因型[J].中华医学检验杂志,1997,20(1):28-31. 被引量:60
  • 2Saunders A M, Strittmatter W J, Schmechel D, et al .Association of apolipoprotein E allele epsilon 4 with late-onset familial and sporadic Alzheimer's disease[J]. Neurology,1993 ,43(8): 1467~1472.
  • 3Myers R H, Schaefer E J, Wilson PW , et al. Apolipoprotein E epsilon4 association with dementia in a population-based study: The Framingham study[J].Neurology. 1996 , 46(3): 673~677.
  • 4Folstein MF, Folstein, SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician[J]. J Psychiatr Res,1975,12(3):189~198.
  • 5Hixson J E,Vernier D T. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI[J]. J Lipid Res, 1990,31(3):545~548.
  • 6Sambrook J. Molecular cloning: a laboratory manual. 3ed. New York: Cold Spring Harbor Laboratory[M].北京:科学出版社,1989. 931~958.
  • 7Richard P, Thomas G, Zulueta MP, et al. Common and rare genotypes of human apolipoprotein E determined by specific restriction profiles of polymerase chain reaction-amplified DNA[J]. Clin Chem, 1994,40:24.
  • 8Iversen L L,Mortishire R J, Pollack S J,et al. The toxicity in vitro of beta-amyloid protein[J]. Biochem J, 1995,311(1):1~16.
  • 9Evans K C, Berger E P,Cho C G,et al. Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease[J]. Proc Natl Acad Sci U S A. 1995 ,31; 92(3): 763~767.
  • 10Hallman D M, Boerwinkle E, Saha N,et al.The apolipoprotein E polymorphism: a comparison of allele frequencies and effects in nine populations[J]. Am J Hum Genet. 1991, 49(2): 338~349.

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