Ghrelin——一种新发现的生长激素释放肽
摘要
Ghrelin是一种新发现的含有28个氨基酸的生长激素释放肽,为生长激素促分泌素受体(Growthhor-monesecretagoguereceptor,GHS-R)的内源性配体。当Ghrelin与其特异性受体(GHS-R)结合后会产生一系列生物学效应。Ghrelin具有刺激垂体前叶释放生长激素、增加食欲、调节能量代谢平衡以及促进胃酸分泌等生物学功能,其作用机理目前尚不清楚。
出处
《饲料博览》
2006年第1期28-30,共3页
Feed Review
参考文献10
-
1Takaya, Ariyasu, Kanamoto, et al. Ghrelin strongly stimulates growth hormone release in humans [J]. Journal of Clinical Endocrinology Metablism, 2000, 85: 4908-4911.
-
2Salfen, Carroll, Keisler, el al. Effects of exogenous ghrelin oil feed intake, weight gain, behaviour, and endocrine responds in weanling pigs [J]. Journal of Animal Science, 2004, 82(7): 1957-1966.
-
3Date Y, Toshinai K, Shuichi K, et al. Peripheral interaction of ghrelin with cholecystokinin on feeding regulation [J]. Endocrinology, 2004, 146(8), 3518-3525.
-
4Hashizume, Horiuchi, Tate, et al. Effects of Ghrelin on growth hormone secretion from cultured adenohypophysial cells in pigs [J].Domest Ani Endocrinol, 2003(24): 209-218.
-
5Kamegal J, Tamura H, Shimizu T, et al. Central effect of ghrelin,an endogenous growth hormone secretagogue, on hypothalamic peptide gene expression [J]. Endocrinol, 2000, 486(3 ): 213-216.
-
6Natazato M, Murakami N, Date Y, ct al, A role for ghrelin in the central regulation of feeding [J]. Nature, 2001, 275: 477-480.
-
7Furuse M, Tachibana T, Ohgushi A, et al. Intracerebroventricular injection of ghrelin and growth hormone releasing factor inhibits food intake in neonatal chicks [J]. Neuroscienee Letter, 2001,301: 123-1268.
-
8Shintani M, Ogawa Y, Ebihara K, et al. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway [J]. Diabetes, 2001 (50):227-232.
-
9Masuda Y, Tanaka T, Inomata N, et al. Ghrelin stimulates gastric acid secretion and motility in rats [J]. Biochemistry Biophysics Research Communication, 2000(76): 905-908.
-
10Date Y, Nakazato M, Murakami N, et al. Ghrelin acts in the central neurons system to stimulate gastri acid secretion [J]. Biochem Biophys Res Commun, 2001, 280( 3 ): 904-907.
-
1徐春兰,汪以真.生长激素释放肽Ghrelin的研究进展[J].中国兽医学报,2006,26(2):222-225. 被引量：2
-
2来景辉,范红结.生长激素释放肽(ghrelin)促生长作用和应用前景[J].动物营养学报,2011,23(7):1085-1088. 被引量：2
-
3雷治海.Ghrelin研究进展[J].畜牧与兽医,2005,37(5):54-57. 被引量：16
-
4来景辉,范红结.生长激素释放肽及其生物学效应[J].中国畜牧兽医,2012,39(11):66-69. 被引量：1
-
5徐春兰,汪以真.生长激素释放肽Ghrelin的研究进展[J].中国畜牧兽医文摘,2006(6):30-30.
-
6杨连玉,杨文艳,耿春银,李德莉,王淑洁,秦贵信.PCI-Ghrelin-28aa质粒对仔猪生长性能的影响[J].中国兽医学报,2009,29(6):797-799. 被引量：1
-
7李振远,李方方,张勇,朱宇旌.胃饥饿素:生物学特征及对动物采食量的调控[J].动物营养学报,2016,28(1):35-42. 被引量：5
-
8张秀文,齐遵利,陈福杰,刘松财,张永亮,任晓慧.生长激素释放肽的研究进展[J].安徽农业科学,2009,37(33):16405-16406.
-
9徐建,陈芳琴,郑德兴,李柯平,冯光德,何建.色氨酸对动物采食的调控[J].饲料研究,2013,36(1):21-24. 被引量：9
-
10王开云,张国生,曾检华,舒邓群.利用生长轴各激素调控动物生长[J].江西畜牧兽医杂志,2008,27(6):4-6. 被引量：3
