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几种天然抗氧化剂对DNA氧化损伤的保护作用 被引量:12

Protection of Several Nature Antioxidants to Oxidative DNA Damage
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摘要 The ability of several nature antioxdants to protect free radical initiator AAPH induced oxidative DNA damage was assessed by measuring the conversion supercoiled pBR322 plasma DNA to the open circular and linear forms.It was found that six nature antioxidants could significantly inhibit the oxidative DNA damage induced by AAPH and their abilities ranked one by one in order as rutin,quercetin and vanillin,ursolic acid,curcumim,oleanolic acid. The ability of several nature antioxdants to protect free radical initiator AAPH induced oxidative DNA damage was assessed by measuring the conversion supercoiled pBR322 plasma DNA to the open circular and linear forms. It was found that six nature antioxidants could significantly inhibit the oxidative DNA damage induced by AAPH and their abilities ranked one by one in order as rutin, quercetin and vanillin, ursolic acid, curcumim, oleanolic acid.
出处 《四川大学学报(自然科学版)》 CAS CSCD 北大核心 2006年第1期238-241,共4页 Journal of Sichuan University(Natural Science Edition)
基金 西北师范大学科技创新工程资助项目(NWNU-KJCXGC-02)
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