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子痫前期患者胎盘组织中VCAM-1和E-Selectin表达的研究 被引量：2

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摘要 目的探讨子痫前期患者胎盘组织中VCAM-1和E-selectin的表达。方法用免疫组化法对20例正常孕妇(对照组)和40例子痫前期患者(子痫前期组,其中轻度16例、重度24例)的胎盘组织进行VCAM-1和E-Selectin定位,并用计算机图像分析系统进行定量分析比较。结果①子痫前期组与对照组比较,VCAM-1和E-Selectin在胎盘绒毛合体滋养细胞的表达,子痫前期组明显低于对照组,两组差异有统计学意义(P<0.05),VCAM-1和E-Selectin在轻度、重度子痫前期患者间的表达差异无统计学意义(P>0.05);②E-Selectin在胎盘绒毛毛细血管内皮细胞的表达子痫前期组明显高于对照组,差异有统计学意义(P<0.05),轻度、重度子痫前期间差异无统计学意义(P>0.05)。结论VCAM-1和E-Selectin可能参与了子痫前期的发病过程。
作者 王瑜 张曦 任琛琛
机构地区 河南省濮阳市妇幼保健院妇产科 郑州大学第三附属医院
出处 《中原医刊》 2006年第4期20-22,共3页 Central Plains Medical Journal
关键词 血管细胞粘附分子-1 E-选择素 胎盘 子痫前期 免疫组织化学
分类号 R714.246 [医药卫生—妇产科学] R972.4 [医药卫生—药品]
  • 相关文献

参考文献5

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共引文献9

同被引文献13

  • 1蔡烟岫,耿淑平,刘曼华,谢晓谦.内皮细胞粘附分子在妊高征发病中的作用[J].南通医学院学报,2004,24(3):263-264. 被引量：3
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引证文献2

二级引证文献1

中原医刊
2006年 第4期

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