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SiRNA-STAT3在肿瘤研究中的应用 被引量:1

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出处 《中国实验诊断学》 2006年第2期210-213,共4页 Chinese Journal of Laboratory Diagnosis
基金 吉林省科技厅资助课题(200505120)
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  • 1Garcia R, Yu CL, Hudnall A, Catlett R, Nelson KL, Smithgall T,et al. Constitutive activation of STAT3 in fibroblasts transformed by diverse oncoproteins and in breast carcinoma cells.Cell Growth Differ 1997; 8: 1267-76.
  • 2Garcia R, Bowman TL, Niu G, Yu H, Minton S, Muro-Cacho CA, et al. Constitutive activation of STAT3 by the Src and JAK tyrosine kinases participates in growth regulation of human breast carcinoma cells. Oncogene 2001; 20: 2499-513.
  • 3Grandis JR, Drenning SD, Chakraborty A, Zhou MY, Zeng Q, Pitt AS, et al. Requirement of STAT3 but not statl activation for epidermal growth factor receptor-mediated cell growth in vitro. J Clin Invest 1998; 102: 1385-92.
  • 4Takemoto S, Mulloy JC, Cereseto A, Migone TS, Patel BK, Matsuoka M, et al. Proliferation of adult T cell leukemia/lymphoma cells is associated with the constitutive activation of JAK/STAT proteins. Proc Natl Acad Sci USA 1997; 94: 13897-902.
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  • 6Leong PL, Andrews GA, Johnson DE, Dyer KF, Sichuan Xi, Mai JC,et al. Targeted inhibition of STAT3 with a decoy oligonucleotide abrogates head and neck cancer cell growth. Proc Natl Acad Sci USA 2003; 100: 4138-43.
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  • 1Maher EA,Fumari FB, Bachoo RM,et al. Malignant glioma:genetics and biology of a wave matter[J]. CAnes Dev,2001,15: 1311.
  • 2Nuria I, Genevieve K, Sidharth V, et al. Identification of a PTEN-regutated STAT3 brain tumor suppressor pathway [ J ]. Genes Dev, 2008,22 : 449.
  • 3Buettner R, Mora LB and Jove R. Activated STAT signaling in human tumors provides novel molecular targets for therapeutic intervention[J]. Clin Cancer Res, 2000,8 : 945.
  • 4Lippman Z, Martienssen R. The role of RNA interference in heterochromatie silencing[J]. Nature,2004,431:364.
  • 5Jaeschke H. Mechanisms of l,iver Injury.II. Mechanisms of neutrophil-induced liver cell injury during hepatic ischemia-reperfusion and other acute inflammatory conditions [ J ]. Am J Physiol Gastrointest Liver Physiol, 2006,290: 1083.

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