摘要
目的:探讨血清CA125水平与不同部位的子宫内膜异位症之间的相关性。方法:选择经手术或腹腔镜确诊的内异症患者63例和排除内异症的对照组30例,按内异症发生部位的不同分为3组:Ⅰ组(卵巢内异组)34例;Ⅱ组(阴道直肠隔内异组)15例;Ⅲ组(腹壁切口内异组)14例。Ⅳ组为对照组,系临床和病理检查排除了内异症的健康者。术前采取空腹静脉血,用化学发光法测定各组血清中CA125水平。结果:(1)卵巢内异组、阴道直肠内异组的血清CA125水平均显著高于对照组(P<0·05);腹壁切口内异组CA125水平显著低于卵巢内异组(P<0·05),而与阴道直肠隔内异症组、对照组比较无统计学差异(P>0·05);(2)以血清CA125≥35U/ml为临界值,CA125诊断各组内异症的敏感性分别为:卵巢内异症52·94%,阴道直肠内异症40·00%,腹壁切口内异症21·43%。诊断特异性为96·67%。结论:CA125在诊断子宫内膜异位症发生方面具有一定的价值,但并不是敏感指标。单凭血清CA125不能鉴别不同部位的子宫内异症。
Objective： To evaluate the relationship between serum CA125 levels and my with endometriosis and 30 control women were collected. Three groups were divided according to the different locations of endometriosis： Group Ⅰ ：ovarian endometriosis ,34 cases; Group Ⅱ ： vagina-rectum endometriosis, 15cases; Group In ： Scar endometriosis, 14 cases. Group Ⅳ was the control group. The serum CA125 levels were measured by chemiluminescence analysis before operation. Results： （1）The serum CA125 levels in ovarian endometriosis and vagina-rectum endometriosis were higher than those in control women （P 〈 0. 05 ）. The serum CA125 levels in scar endometriosis were lower than those in ovarian endometriosis （P 〈0. 05）. （2）If the diagnosis standard of endometriosis by CA125 was above 35U/ ml ,the sensitivity was 52.94% of ovarian endometriosis,40. 00% of vagina-rectum endometfiosis,21.43% of scar endometriosis respectively, and the specificity was 96. 67%. Conclusion： The serum CA125 testing for diagnosis of endometfiosis may have considerable value, but it is not a sensitive marker. The accuracy of using only CA125 testing for diagnosis of endometriosis in different locations is limited.
出处
《现代妇产科进展》
CSCD
北大核心
2006年第1期39-41,共3页
Progress in Obstetrics and Gynecology
