摘要
目的:应用药动学理论指导临床合理用药。方法:对基本药动学公式进行拓展和转换,得到临床实用的新公式;创建实用药动学参数表,应用该表得到临床需要的药动学参数。结果:有了实用药动学参数表,随时可考察临床用药的合理性,结合血药浓度监测,可做到用药个体化。结论:实用药动学参数表可作为指导个体化用药的重要工具。
OBJECTIVE： To direct rational use of drugs in the clinic by applying pharmacokinetic theory. METHODS： A new formula practicable for clinic was derived by expanding and transforming the basic pharmacokinetic formula. A practical pharmacokinetic parameter table was established and from which the pharmacokinetic parameters needed by clinic were available. RESULTS： With the help of practical pharmacokinetic parameter table, the rationality of clinical medication can be investigated at any time. Combined with monitoring of blood concentration, personalized medicine can be realized. CONCLUSION ：The practical pharmacokinetic parameter table is an important tool in directing personalized medicine.
出处
《中国药房》
CAS
CSCD
北大核心
2006年第4期276-278,共3页
China Pharmacy
关键词
药动学参数
参数表
用药个体化
Pharmacokinetic parameters
Parameter tables
Personalized medicine
