复方甘草酸苷治疗慢性乙型肝炎疗效观察

Observation of Therapeutic Effect of Compound Glycyrrhizin on Chronic Type B Hepatitis

目的:观察复方甘草酸苷治疗慢性乙型肝炎的疗效。方法:126例慢性乙型肝炎患者随机均分为对照组和治疗组,对照组给予一般退黄、护肝治疗,治疗组在对照组治疗基础上加用复方甘草酸苷,2组疗程均为8wk。结果:治疗组总有效率为93·6%,对照组总有效率为33·3%,组间有显著性差异(P<0·01);治疗组临床症状、体征改善率及肝功能改善情况明显好于对照组(P<0·05)。结论:复方甘草酸苷治疗慢性乙型肝炎安全、有效。

OBJECTIVE：To observe the effect of compound glycyrrhizin on patients with chronic type B hepatitis.METHODS： 126 patients with chronic type B hepatitis were randomly divided into two groups： the control group was administered with common therapy like reducing jaundice and protecting liver; the trial group was administered with compound glycyrrhizin plus the therapy of the control group .Time of therapy for both groups was 8wk.RESULTS：The total effective rates for the trial group and the control group were 93.6% and aa a% ,respectively,and significant differences were noted between groups（P〈 0.01） .The clinic symptorns,physical signs and liver functions of trial group had a better amelioration than the control group（P〈 0.05） .CONCLUSION ：Compound glycyrrhizin is safe and effective in the treatment of chronic type B hepatitis.