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小剂量茶碱联合吸入糖皮质激素治疗咳嗽变异型哮喘疗效分析 被引量:2

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摘要 目的观察小剂量茶碱联合吸入糖皮质激素治疗咳嗽变异型哮喘的疗效。方法26例咳嗽变异型哮喘患者均停用抗生素及其它止咳祛痰药物,口服茶碱控释片(商品名:浪宁)100mg,每日2次,同时吸入必可酮250μg,每日2次,观察治疗前后咳嗽症状的改善情况,肺功能测定(FEV1、FVC、PEFR)及PEFR日间变异率。结果26例患者治疗后2周咳嗽症状明显改善,总有效率为88.5%,治疗后8周肺功能显著改善,FEV1、FVC、PEFR较治疗前升高(P<0.05),尤其PEFR日间变异率较治疗前明显降低(P<0.01)。结论小剂量茶碱联合吸入糖皮质激素治疗咳嗽变异型哮喘疗效显著,明显改善肺功能和降低气道高反应性,值得临床推广应用。
作者 陈虹 苏伟强
出处 《海南医学》 CAS 2006年第3期100-101,共2页 Hainan Medical Journal
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