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直肠癌局部切除25例疗效观察 被引量:7

Clinical Study on 25 Patients With Rectal Cancer Treated By Lo cal Excision.
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摘要 目的探讨经肛门局部切除治疗直肠癌的效果。方法对25例直肠癌行经肛门局部切除术(T1期11例,T2期14例),T2期患者术后辅助放疗,随访时间1~10.1年,平均5.1年。结果4例局部复发,2例死于远处转移,5年生存率为92%,T1期100%,T2期86.67%(P〉0.05);局部复发率为16%,T1期和B期患者分别为9.09%和21.43%(P〉0.05)。结论经肛门局部切除治疗直肠癌适于T1~T2N0M0,组织分化好的肿瘤,术后放疗是控制T2期患者术后局部复发的关键。 Objective To evaluate the results of transanal local excision for rectal carcinoma. Methods 25 patients with rectal cancers underwent local excision in our hospital (T1: 11and T2: 14), all patients of T2 tttmors received adjuant radiation therapy.Mean follow- up time was 5.1 years after local excision. Results Five- year overall survival rate was 92 percent, 100 percent for T1 tumors and 86.67 percent for T2 tumors ( P 〉 0.05) .Five - year local recurrence rate was 16 percent, 9.09 percent for T1 tumors and 21.34 percent for T2 tumors ( P 〉 0.05) .Conclusion Transanal local excision for rectal cancer might only be successfully performed in selected patients (T1~T2N0M0, well moderately - differentiated carcinoma) . Postoperation adjuant radiation therapy is the main paints for T2 patients to controll local recurrence.
作者 张伟军 李锋
出处 《医学研究杂志》 2006年第2期45-46,共2页 Journal of Medical Research
关键词 直肠癌 局部切除术 放射治疗 Rectal carcinoma Local excision Radiotherapy
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参考文献4

  • 1[1]Chandler PJ,Okin B.Rectal carcinoma:operative treatment.In:Beck DE,Wexner SD,eds Fundamentals of anorectal surgery[M].Philadelphia; WB Saunders,1998,301 -367.
  • 2[2]Wexner SD,Rotholtz NA.Surgeon influenced variables in resectional rectal cancer surgery[J].Dis Colon Rectum,2000,43 (5):1606-1627.
  • 3[3]Graham RA,Hackford AW,Wazer DE.Local excision of rectal carcinoma.; a safe alternative for more advanced tumor[J].J Surg Oncol,1999,70 (4):235-240.
  • 4刘瑞宝,于树江,曲丽英,赵家宏,鄢风昌.直肠癌术前CT分期方法及其应用[J].实用肿瘤学杂志,1996,10(1):31-32. 被引量:6

二级参考文献1

  • 1Dr. Brenda Shank M.D., Ph.D.,D. David Dershaw M.D.,James Caravelli M.D.,Jay Barth M.D.,Warren Enker M.D.. A prospective study of the accuracy of preoperative computed tomographic staging of patients with biopsy-proven rectal carcinoma[J] 1990,Diseases of the Colon & Rectum(4):285~290

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