电针对大鼠局灶性脑缺血再灌注大脑皮层超微结构形态学损伤的保护作用

Reducing Effect of Electroacupuncture on Morphological Injury to the Corticocerebral Ultrastructure in Rats with Focal Cerebral Ischemia and Reperfusion

目的探讨电针“百会”、“大椎”穴对SD大鼠局灶性脑缺血再灌注大脑皮层超微结构形态学损伤的保护作用。方法线栓法闭塞SD大鼠大脑中动脉,制备局灶性脑缺血再灌注模型。透射电镜观察大脑皮层超微结构,并对线粒体进行体视学检测。结果模型组大脑皮层超微结构损害明显,电针组大脑皮层超微结构明显改善。两组线粒体体视学检测结果有极显著差异,P<0.01。结论电针“百会”、“大椎”穴对SD大鼠局灶性脑缺血再灌注大脑皮层超微结构形态学损伤具有明显的保护作用。

Projective To investigate the reducing effect of eleetroacupuncture of points Baihui and Dazhui on morphological injury to the corticocerebral ultrastructure in SD rats with focal cerebral isehemia and reperfusion. Methods A SD rat model of focal cerebral ischemia and reperfusion was made by occlusion of the middle cerebral artery with thread. The corticocerebral ultrastructure was examined by transmission electron microscopy and the mitochondria, stereologically. Results The cortieocerebral ultrastructure was significantly injured in the model group and significantly improved in the eleetroacupuncture group. There was a very significant difference in the result of the stereologieal examination of mitochondria between the two groups （P 〈 0.01 ）. Conclusion Electroacupuneture of points Baihui and Dazhui has a marked reducing effect on morphological injury to the corticocerebral ultrastructure in SD rats with focal cerebral ischemia and reperfusion.