胸水及血癌胚抗原在鉴别良恶性胸腔积液中的作用

Action of CEA of Pleural Fluid and Serum in Differential Diagnosis of Benign or Malignant of Pleural Effusion

目的探讨血清及胸水癌胚抗原在鉴别良恶性胸腔积液中的作用。方法放射免疫法测定胸腔积液患者血清及第1次胸水中的癌胚抗原含量。结果良性胸腔积液患者血清及胸水中的癌胚抗原均在正常范围,且胸水癌胚抗原/血清癌胚抗原<1。恶性胸腔积液患者血清癌胚抗原可正常或升高,胸水中癌胚抗原升高,胸水癌胚抗原/血清>1。结论同时检测血清及胸水中癌胚抗原含量,可以作为鉴别良恶性胸腔积液的指标。

Objective To discuss the action of CEA in serum and pleural fluid in differential diagnosis whether the pleural effusion is benign or malignant. Methods The CEA content in serum and in pleural cavity extracted first time were detected with radio - immunity method. Results The CEA in serum and in pleural fluid of benign were in normal range with ratio of CEAp/CEAs less than 1. The CEA in serum was normal or higher in malignancy, CEA in pleural fluid was higher than normal with ratio more than 1 of CEAp/CEAs. Conclusion The detection of CEA simultaneously in both serum and pleural effusion might be the data to differentiate the diagnosis of benign or malignancy.