利用基因工程提高植物维生素E营养品质的策略

Improving the vitamin E nutrition of plant by gene engineering

维生素E是一种对植物、动物和人类都具有重要作用的脂溶性维生素。而植物则是人类维生素E的主要来源。对维生素E的结构和合成途径进行了简单的介绍,并重点综述了利用基因工程提高植物维生素E营养品质的策略。这些策略主要包括导入编码影响维生素E总量相关酶的基因来提高维生素E的总量;导入编码影响维生素E组成相关酶的基因,提高α-生育酚在总生育酚中所占的比例,从而提高维生素E的活性。

Vitamin E is an important class of lipid-soluble compounds with antioxidant activities that play a very important role in plant,animal and human being. Plant is the main resource of the vitamin E, Based on presenting a brief summary of the structure and biosynthesis pathway of vitamin E, the particular emphasis was placed on the methods that used to improve the vitamin E nutrition of plant by gene engineering in this review, This includes two complementary strategies： （i）Introducing the genes with encoding enzymes can increase the flux through the tocopherol biosynthetic pathway to produce elevated levels of total tocols; （ii）Introducing the genes which encoding enzymes can affect the composition of tocols and make α-tocopherol the predominant form of vitamin E,so the activity of vitamin E is elevated.