铁剂在治疗口腔白色念珠菌病中作用的研究

The study of chalybeate therapy in oral candidiasis albicans

目的探讨缺铁性贫血与口腔白色念珠菌病间的关系,以及补铁在治疗口腔白色念珠菌病中的作用。方法对145例确诊为口腔白色念珠菌病的患者行血液学检查,将其中46例患有缺铁性贫血者随机分为两组,对照组采用常规抗真菌治疗,实验组采用抗真菌联合补铁治疗。结果145例口腔白色念珠菌病患者中有46例合并缺铁性贫血(31.7%)。实验组近期疗效与对照组无显著性差异(P>0.05),远期疗效明显优于对照组(P<0.05)。结论缺铁性贫血是口腔白色念珠菌病的一个重要诱因,对于合并缺铁性贫血的口腔白色念珠菌病患者,联合补铁治疗能够显著提高远期治愈率。

Objective To study the relationship between iron deficiency anemia and oral candidiasis albicans, and the role of chalybeate in treating oral candidiasis albicans. Methods One hundred and forty -five cases with oral candidiasis albicans were examed hematologic indexes. Dividing the 46 patients with iron deficiency anemia meanwhile into two groups randomly. The control group was treated with anti-fungus drugs, while the experimental group was given anti-fungus drugs and chalybeate. Results Forty-six patients had iron deficiency anemia in the 145 cases with oral candidiasis albicans（31.7 % ）. The effect of the experimental group was not significantly different from that of the control（ P 〉0.05） in the near future , but obviously better （ P 〈 0.05） in long-term. Conclusion Iron deficiency anemia is an important cause of oral candidiasis albicans. Application of chalybeate can improve the cure rate long-term results in oral candidiasis patients with iron deficiency anemia.