上颌窦鳞状细胞癌核仁组成区相关嗜银蛋白的检测

AN INVESTIGATION OF NECLEOLAR ORGANIZER REGION ASSOCIATED ARGYROPHLIC PROTEINS IN SQUAMOUS CELL CARCINOMA OF THE MAXILLARY SINUS

目的：观察上颌窦鳞状细胞癌核仁组成区相关嗜银蛋白（ＡｇＮＯＲｓ）的改变。方法：采用胶银染色法对２６例上颌窦鳞状细胞癌进行ＡｇＮＯＲｓ检测。结果：①上颌窦鳞状细胞癌ＡｇＮＯＲｓ计数较对照组增高；②不同分化程度的上颌窦鳞状细胞癌细胞ＡｇＮＯＲｓ计数不同。结论：检测ＡｇＮＯＲｓ是上颌窦鳞状细胞癌诊断中的有价值的方法。

Objectives To study the changes of necleolar organizer region associated argyrophlic proteins(AgNORs)in squanous cell carcinoma of the maxillary sinus.Methods: AgNORs of squanous cell carcinoma of the maxillary sinus in 26 patients were measured with silver colliod staining technique. Results: ①The number of AgNORs was significantly higher in squamous cell carcinoma of the maxillary sinus than of the controls. ②number of AgNORs varied significantly in the different grades of squamous cell carcinoma of the maxillary sinus. Conclusions: The investigation of AgNORs is of value in the diagnosis of sqamous cell carcinoma of the maxillary sinus.