慢性湿疹和皮炎122例斑贴试验结果分析

Clinical analysis of the patchtest in 122 cases of chronic eczema and dermatitis

目的:探讨慢性湿疹和皮炎患者接触性致敏原及其特点。方法:应用斑贴试验分析122例慢性湿疹和皮炎患者接触性致敏原。结果:列前10位的常见致敏原分别是0.1%硫柳汞、5%硫酸镍、7%芳香混和物、1%甲醛、1%肉桂醇、1%促进剂D、1%氯化钴、20%松香、25%秘鲁香油、3%卡巴混和物;引起手部湿疹和皮炎患者的致敏原主要为0.1%硫柳汞和7%芳香混和物,躯干、四肢湿疹和皮炎患者的致敏原主要为5%硫酸镍和0.1%硫柳汞,面部湿疹和皮炎患者的致敏原主要为0.1%硫柳汞和1%甲醛,脐周皮炎患者的致敏原主要为5%硫酸镍。结论:斑贴试验有助于明确慢性湿疹和皮炎患者的接触性致敏原及其性质。

Objective： To explore the characteristics of contact allergens in chronic eczema and dermatitis. Methods： one hundred and twenty two cases of chronic eczema and dermatitis were tested with a standardized patchtesting technique against contact allergens. Results： Data from these patients showed that the top 10 allergens were as follows： 0.1% thimerosal, 5% nickel sulfate, 7% fragrance mix, 1% formaldehyde, 1% cinnamic alcohol, 1% DPG, 1% cobalt chloride, 20% resin, 25% balsam of Peru, 3% Carba mix. The allergens causing eczema and dermatitis of hands were： 0.1% thimerosal and 7% fragrance mix, those for trunk and limbs were： 5% nickel sulfate and 0.1% thimerosal, those for the face were： 0.1% thimerosal and 1% formaldehyde, and that for navel eczema was： 5% nickel sulfate. Conclusion： Patchtesting is helpful in identifing the property of contact allergens in chronic eczema and dermatitis.