摘要
1997年美国糖尿病学会(ADA)提出空腹血糖受损(IFG)的概念,2003年11月ADA提出IFG下限诊断标准从6.1mmol/L下调到5.6mmol/L。IFG与糖耐量减低(IGT)人群进展为2型糖尿病的危险均较正常血糖人群高,但两者的表现谱却存在许多差异,如两者的患病率具有性别及种族差异;胰岛素分泌及胰岛素抵抗状况也不同;两者与血管病变的关系及血管病变的发生率和病死率也有差异。因此,基于IFG、IGT的病理生理学应对其采取相应的干预措施。
The concept of impaired fasting glucose（IFG） was firstly raised in 1997, and the fasting glucose level of the diagnostic criteria of IFG was lowered from 6.1 mmol/L to 5.6 mmol/L in 2003 by ADA. Both IFG and impaired glucose tolerance（IGT） have higher risk of diabetes than normal glucose tolerance, but they also have many different profiles, such as their prevalence in different sex and races, their state of insulin secretion and insulin resistance, their relationship with vascular diseases and the incidence and mortality of vascular diseases. So some actions should be taken for IFG and IGT based on their pathophysiology.
出处
《国际内分泌代谢杂志》
2006年第1期5-8,共4页
International Journal of Endocrinology and Metabolism
关键词
空腹血糖受损
糖耐量减低
胰岛素分泌
胰岛素抵抗
血管病变
糖尿病
Impaired fasting glucose
Impaired glucose tolerance
Insulin secretion
Insulin resistance
Vascular disease
Diabetes
