超鞭毛虫支气管肺感染二例报告及文献复习

Clinical analysis of bronchopulmonary infection with hypermastigotes:a report of two cases and review of the Chinese literature

目的提高对超鞭毛虫支气管肺感染临床诊断认识。方法报道2例超鞭毛虫支气管肺感染,并结合国内文献中报道的6例患者的临床资料进行分析。结果下呼吸道超鞭毛虫感染多发生在南方湿热地区,临床症状轻重差异较大,可表现为慢性咳嗽、支气管哮喘(简称哮喘),也可引起肺炎、肺脓肿。呼吸道分泌物涂片查见虫体是确诊的依据,甲硝唑等药驱虫治疗对大多数患者有效。结论对不明原因的咳嗽、哮喘、肺炎、肺脓肿的患者,在治疗效果不佳,且以常见病难以解释时要注意少见病原体感染的可能。

Objective To describe the clinical features of brenchopulmonary infection with hypermastigotes. Methods Two cases of bronchopulmonary infection with hypermastigotes were reported. The clinical features of another six cases from the Chinese literature were reviewed. Results Brenchopulmonary infection with hypermastigotes mostly occurs in the hot and humid southern area. The symptoms are severe ,with different manifestations such as chronic cough, asthma, pneumonia, and even lung abscess. Final diagnosis is made by the presence of hypermastigotes in smears of secretions from the respiratory tract. An antiprotozoal such as metronidazole is always effective. Conclusion In patients with unexplained cough, asthma, and pneumonia or lung abscess which do not respond to ordinary therapy, rare pathogens such as hypermastigotes need to be considered.