超声介入硬化治疗大块型、巨块型肝血管瘤的远期疗效

Long-term effect of interventional sclerotherapy under the guidance of ultrasound on large and massive hepatic hemangioma

目的 研究超声介入硬化治疗肝血管瘤大块型、巨块型的临床价值和远期疗效。方法 在超声引导下经皮肝穿刺由里向外，多点、多面向瘤体内注入硬化剂，按瘤体体积公式计算注药量，设计分次注药量。结果 穿刺治疗3750例，消失率、基本消失率分别为大结节型98．45％、1．55%；大块型30．25％、31．65％；巨块型5．1％、0，巨块型中瘤体直径缩小1/2～2／3者占94．9％。穿刺治疗总有效率100％。并发肝内出血0．133％。结论 超声介入治疗肝血管瘤大结节型、大块型为最佳治疗期，疗效满意，瘤体消失率高。远期观察无复发，对肝、肾功能无损伤，可达康复之目的。

Objective To evaluate the clinical effectiveness and long-term effect of interventional sclerotherapy under ultrasonographic guidance on large and massive hepatic hemangioma. Methods The sclerosant was injected into the hemangioma from different spnts and directions under the guidance of ultrasound. The dose of drug was based on the volume of hemangioma and planned to inject in different times. Results A total of 3750 patients, the disappearance rate and basic disappearance rate was 98.45%, 1.55% in nodules; 30.25%, 31.65% in the large. 5.1%, 0 in the massive, and the contracture was 1/2--2/3 in 94.9% in massive hemangioma. The total effectiveness rate was 100%, and the complication rate of bleeding in liver was 0. 134%. Conclusion Interventional sclerotherapy for large nodules and large hemangioma were the best period of treatment. No recurrence was shown and no harm to liver, kidney function in long-term observation. This is an effective therapy for hepatic hemangioma.