摘要
本文报告用胡芦素片合并化疗药物治疗原发性肝癌44例,治后一年生存率47.7％(21/44),中位生存期12个月,平均生存期12.5±7.54月,比同期单用同一化疗方案对照组—一年生存率9％(4/44),中位5月,平均6.1±7.12月,有非常显著差异(P<0.01)。且胡芦素组尚有8例存活,而后者仅2例。胡芦素片提取自中药甜瓜蒂(Cucumis melo),动物实验表明有护肝、抑癌、抗肝纤维增加和提高免疫功能作用,或与抗癌药并用有协同作用而增加疗效。
Dining 1984-1986, 44 patients of primary liver cancer were treated with Cucurbitacin (extracted from Cucumis melon) plus Mitomycin, 5-Fluoro.uraciL, Camptothecin and/or Adriamycin. The 1-year survival rates was 47.7% (21/44). The median survivals were 12 months and the mean survival 12.5±7.54 months. This is better than the control group treated by the same chemotherapy regimen without Cucurbitacin during the same period of time. The difference was significant (p<0.01).
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1989年第6期434-437,共4页
Chinese Journal of Cancer
