1Aljada A, Gard R, Ghanim H, et al. Nuclear factor-kB suppressive and inhibitor-kB stimulatory effects of troglitazone on obese patients with type 2 diabetes: evidence of an anti-inflammatory action? J clin Endocrinol Metab,2001,86(7):3 250-3 256.
2Friedman JM, Halaas JL. Leptin and the regulation of body weight in mammals. Nature, 1998,395: 763.
3Tsigosc, Papanicolaou DA, Kyrou I, et al. Dose-dependent effects of recombinant human interleukin-6 on glucose regulation. J clin Endocrinol Metab, 1997,82:4 167-4 170.
1Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med, 1999, 340:115～126.
2Fernandez-Real JM, Ricart W. Insulin resistance and inflammation in an evolutionary perspective: the contribution of cytokine genotype/phenotype to thriftness. Diabetologia, 1999, 42:1 367～1 374.
3Aljada A, Gard R, Ghanim H, et al. Nuclear factor-kB suppressive and inhibitor-kB stimulatory effects of troglitazone on obese patients with type 2 diabetes: evidence of an anti-inflammatory action? J Clin Endocrinol Metab, 2001, 86(7): 3 250～3 256.
4Dandona P, Aljada A. A rational approach to pathogenesis and treatment of type 2 diabetes mellitus, insulin resistance, inflammation, and atherosclerosis. Am J Cardiol, 2002, 90(5A):27G～33G.
5Iwamoto Y, Nishimura F, Nakagawa M, et al. The effect of antimicrobial periodontal treatment on circulating tumor necrosis factor-alpha and glycated hemoglobin level in patients with type 2 diabetes. J periodontal, 2001, 72(6):774～778.
6Hundal RS, Petersen KF, Mayerson AB, et al. Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes. J Clin Invest, 2002, 109(10):1 321～1 326.
7Reaven GM. Role of insulin resistance in hunan disease. Diabetes, 1988, 37:1 595～1 607.
8Wajchenberg BL, Malerbi DA, Rocha MS, et al. Stndrome X: a syndrome of insulin resistance. Diabetes Metab Rev, 1994, 10:19～29.
9Pickup JC, Mattock MB, Chusney GD, et al. NIDDM as a disease of the innate immune system: association of acute phase reactants and interleukin-6 with metabolic syndrome X. Diabetologia, 1997, 40: 1 286～1 292.
10Schmidt MI, Duncan BB, Sharrett AR, et al. Markers of inflammation and prediction of diabetes mellitus in adults ( Atherosclerosis Risk in Communities study): a cohort study. Lancet, 1999, 353:1 649～1 652.
