期刊文献+

竞技运动与基因兴奋剂 被引量:6

Gene Doping in Sports
下载PDF
导出
摘要 基因兴奋剂是指非治疗目的应用以提高运动能力的基因、遗传元件或细胞。随着分子遗传学、体细胞遗传学、细胞生物学、分子病毒学等学科的重大发现和技术进步,基因治疗不仅用于治疗疾病,也有用于提高人体运动机能的可能。为了保证运动员的身体健康及竞技比赛的公正性,国际奥委会、世界反兴奋剂协会和国际运动联盟已经将基因兴奋剂列入违禁药。 Gene or cell doping is defined by the World Anti-doping Agency (WADA) as “the non-therapeutic use genes, genetic elements and/or cells that have the capacity to enhance athletic performance”. New research in genetic and genomics will be used not only to diagnose and treat disease, but also to attempt to enhance human performance. To protect the health of athletes and to ensure equal competitive conditions, the international Olympic Committee, WADA and International Sports Federations have accepted performance-enhancing substances and methods as being doping, and forbidden them.
作者 王玉
出处 《成都体育学院学报》 CSSCI 北大核心 2006年第1期96-99,共4页 Journal of Chengdu Sport University
关键词 兴奋剂 基因治疗 运动 doping gene therapy sports
  • 相关文献

参考文献18

  • 1Parsa CJ,Koch WJ.Gene interventions in the bata-adrenergic system for treating heart failure[J].Semin Thorac Cardiovasc Surg,2003,15(3):259-267.
  • 2Maurice JP,Hata JA,Shah AS,et al.Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery[J].Clin lnvest,1999,104(1):21-29.
  • 3Williams ML,Hata JA,Schroder J,et al.Targeted beta-adrenengic receptor kinase(betaARKl)inhibition by gene transfer in failing human hearts[J].Circulation,2004,109(13):1590-1593.
  • 4Bemecker OY,Monte F,Hajjar RJ.Gene therapy for the treatment of heart failure-calcium signaling[J].Semin Thorac Cardiovasc Surg,2003,15(3):267-276.
  • 5Most P,Pleger ST,Volkers M,et al.Cardiac adenoviral S100A1 geng delivery rescues failing myocardium[J].Clinlnvest,2004,114(11):1550-1563.
  • 6Huq F,Lebeche D,LyerV,et al.Gene transfer of parvalbumin improves diastolic dysfunction in senescent myocytes[J].Circulation,2004,109(22):2780-2785.
  • 7Leotta E,Pateiunas G,Murphy G,et al.Gene therapy with adenovirus-mediated myocardial transfer of vascular endothelial growth factor 121 improves cardiac pertormance in a pacing model of congestive heart failure[J].JThorac Cardiovasc Surg,2002,126(6):1101-1103.
  • 8Jin H,Wyss JM,Yang R,et al.The therapeutic potential of hepatocyte growth factor for myocardial infrarction and heaet failure[J].Curr Pharm Des,2004,10(20):2525~2533.
  • 9Takahashi K,Ito Y,Morikawa M,et al.Adenoviral-delivered angiopoiedn-l reduces the intarction and attenuates the progtession of cardiac dysfunction in the rat model of achte myocardial infarction[J].Mol Ther,2003,8(4):584-592.
  • 10Penny WF,Hammond HK.Clinical use of intracoronary gene transfer of fibroblast growth factor for coronary artery disease[J].Curr Gene Ther,2004,4(2):225-230.

同被引文献43

引证文献6

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部