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精子DNA完整性的检测及其在辅助生殖技术中的作用 被引量:9

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摘要 辅助生殖技术(ART)中,卵胞浆内单精子注射(ICSI)的出现开创了治疗男性不育的新局面,同时使得精子DNA完整性倍受人们关注。精子DNA完整性对自然受孕、人工授精、胚胎、胎儿、婴儿乃至成人的发育至关重要。研究表明精子DNA完整性是优于常规精液分析的独立参数,与ART结局有很高的相关性。因此精子DNA完整性检测对于ART有很重要的意义。目前有多种方法检测精子DNA完整性。
作者 李刚 孙莹璞
出处 《生殖与避孕》 CAS CSCD 北大核心 2005年第11期690-693,共4页 Reproduction and Contraception
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