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E-钙黏蛋白与肺部肿瘤 被引量：1

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摘要 E-钙黏蛋白(E-cadherin,E-cad)是一种介导细胞-细胞间相互黏附、具有维持组织结构完整性和极性的钙依赖性跨膜糖蛋白。E-钙黏蛋白与连接素构成复合体(E-cadherin-catenin,E-cad-cat)依赖于钙和其它分子来发挥作用。较多研究证实E-cad与多种上皮型恶性肿瘤的分化、侵袭、转移、预后有关。E-cad与肺部肿瘤亦有一定关系,本文就E-cad的结构、生物学特性、调节机制以及与肺部肿瘤的关系做一综述。
作者 王海娇 曲成毅 丁毅鹏
机构地区 山西医科大学 山西医科大学公共卫生学院 海南农垦总局医院
出处 《国际呼吸杂志》 2006年第2期95-98,共4页 International Journal of Respiration
关键词 E-钙黏蛋白 细胞黏附 E-钙黏蛋白基因 肺部肿瘤
分类号 R734.2 [医药卫生—肿瘤]
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参考文献27

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国际呼吸杂志
2006年 第2期

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