OG TT、IRT和CPRT联检在DM2诊治中的价值

Combined Application of OGTT,IRT and CPRT for Diagnosis and Treatment of Type 2 Diabetes Mellitus

目的:评价口服葡萄糖耐量试验(OGTT)、胰岛素释放试验(IRT)和C-肽释放试验(CPRT)联合应用在糖尿病(DM)诊断和治疗中的价值。方法:选用已进行上述三种试验的217例受检者资料进行回顾性分析。结果:①在可疑DM人群中,未诊断、未治疗的DM2病人占69%(49/71),其中空腹血糖(FPG)正常者占53%(26/49)。②以2hPG筛查DM,只有8%(4/49)的病人可能会漏诊。③糖尿病治疗达到控制标准者占24%(35/146)。结论:OGTT、IRT和CPRT联合应用可提高诊断准确性,降低漏诊率,并能够指导临床治疗。

Objective To assess the value of combined clinical application of orsl glucose tolerance test （ OGTT）, insulin release test （IRT） and C - peptide release test （CPRT） for the diagnosis and treatment of type 2 diabetes mellitus （DM2）. Methods Retrospect anal. ysis of the data of the results of these three tests in 217 subjects examined was performed. Results ① Among the 217 subjects, 71 of them were not diagnosed as diabetics. However, upon luther scrutization of the data, 49 （69%） should be classified as diabetics. Fasting blood sugar （FPG） levels were normal in 53% of the 49, but 2h PG levels were mostly elevated with the exception of only 4 （4/49, 8% ）, Therefore, 2h PG levels were much more useful for screening of diabetes than FPG levels were. ② Treatment result in these patients was not very satisfactory： only 24% of the patients （35/146） had their disease well -controlled. Conclusion Combined clinical application of OGTT, ITB and CPBT would enhance the diagnostic accuracy of diabetes with fewer eases missed.