N-取代-5-磺酰基吡唑肟醚衍生物的合成及生物活性研究

Synthesis and Biological Activity of N-Substituted-5-Sulfonyl Pyrazole Oime Ether Derivation

以吡唑酮、盐酸羟胺、硫酚、2-氯-5-氯甲基吡啶等化合物为原料,设计合成了5个未见文献报道的磺酰基吡唑肟醚新化合物,其结构经元素分析、1HNMR、IR和MS验证。初步生物活性测试表明,部分化合物具有一定的杀菌活性。

Five new compounds were synthesized with pyrazolone, thiophenol and hydroxylamine hydrochlofide. Their structures were identified by IR, ^1H NMR, MS and elemental analysis. Preliminary hioassays indicated that some compounds showed fungicidal activity.