白术挥发油化学成分的GC/MS分析

Studies on chemical constituents of the essential oil of Atractylodes macrocephala Koidz by GC/MS

目的:鉴定中药白术挥发油的化学成分。方法:按照中国药典1995年版规定的方法提取白术挥发油,采用 GC/MS 联用仪分析其挥发油的化学成分。结果:共分离出77个组分,鉴定了其中46个成分,占挥发油总量的94.86%,其中含量高于1%的有11个,并且以苍术酮(atractylone)含量最高(43.7%),其他10个主要是萜类化合物。结论:本法分离效果良好,所鉴定组分较准确,对白术挥发油的开发应用研究有一定的参考价值。

Objective ：To identify the compositions of essential oil from Atractylodes macrocephala Koidz. Method： The essential oil was extracted from Atractylodes macrocephala Koidz through steam distillation method according to 1995 edition of Chinese pharmacopoeia. GC/MS was used for the determination of essential oil. Results：46 among the 77 separated constituents were identified, which constituted 94.86% of the total amount, the contents of 11 compounds were over 1%. Atractylon wax was the richest（43.7% ）, other 10 important components were characterized to be terpenes. Conclusion：The experiments conducted in our laboratory with the essential oil show that it is a simple, rapid, efficient, inexpensive and with good repeatability and recovery. It is excellent to separate and determine the component of essential oil from Atractylodes macrocephala Koidz, and offer reference value in the development and application study of the volatile oil.