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NOD1、NOD2:两个重要的天然免疫胞内识别受体 被引量:9

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摘要 机体对微生物入侵的免疫炎症应答过程中模式识别受体(patternrecognitionreceptors,PRRs)是启动机体天然免疫应答机制的关键,主要在获得性免疫系统被活化之前发挥抗感染作用。NOD1和NOD2这两个蛋白分子作为一种新的胞内识别受体参与了细胞凋亡和核因子NF-κB的活化,并与一些炎症性疾病密切相关,在天然免疫中发挥了重要的作用。
出处 《国际免疫学杂志》 CAS 2006年第1期23-26,共4页 International Journal of Immunology
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