几种药物联合治疗煤工尘肺合并慢性肺源性心脏病疗效观察

Observation of the Curative Effect of a Combination of Drugs in Treating Pneumoconiosis Combined with Chronic Pulmonary Heart Disease

目的 探索煤工尘肺慢性肺心病急性加重期的治疗方法，以减少并发症、降低死亡率。方法 将80例患者随机分为两组。所有患者均接受内科常规基础治疗（吸氧、祛痰、平喘、控制感染、利尿等）；观察组在常规治疗的基础上采用卡托普利、硝酸甘油、多巴胺联合治疗，7．10d为1疗程。结果治疗组显效率为52．5％，对照组显效率22．5％。两组治疗显效率比较差异具有显著性（P〈0．05）。结论 三药联合治疗煤工尘肺合并慢性肺源性心脏病急性加重期疗效明显，值得临床应用。

[Objective] To explore a method of treating pneumoconiosis combined with chronic pulmonary heart disease in the acute severstage and reduce the incidence of complications and mortality. [Methods] 80 cases were randomly divided into two groups and receive common treatment; the treatment group also received combined treatment with captopfil, nitroglycerin and dopamine for 7-10 days. [Results] The effectual rate of the treatment group was 52.5%, that of the control group was 22.5%, the difference was significant （ P 〈 0.05）. [ Conclusion] The combined treatment with the three drugs has been proved to be obviously effective and is worthy of clinical application.