痰热清注射液治疗社区获得性肺炎50例疗效观察

Treatment of Community Acquired Pneumonia by Tanreqing Injection:A Clinical Observation of 50 Cases

目的:观察痰热清注射液治疗社区获得性肺炎(CAP)的临床疗效。方法:将100例CAP患者随机分为治疗组与对照组各50例。2组均给予西医常规治疗,治疗组加用痰热清注射液。观察2组临床疗效及治疗前后白细胞计数(WBC)、血清超氧化物歧化酶总活力(T-SOD)及血清丙二醛(MDA)等指标的变化。结果:愈显率治疗组为88％,对照组为62％,2组比较,差异有非常显著性意义(P<0．01)。治疗后治疗组第1天体温已经明显下降,2天已基本降至正常,3天体温已完全正常,与对照组同时段比较,差异有非常显著性意义(P<0．01)。治疗组治疗后WBC第1天开始明显下降,2天已降至正常,与治疗前比较,差异有非常显著性意义(P<0．01);与对照组同时段比较,差异有非常显著性意义(P<0．01)。治疗后2组T-SOD、MDA均有所改善,与治疗前比较,差异有显著性或非常显著性意义(P<0．05,P<0．01);治疗后治疗组与对照组比较,差异有显著性或非常显著性意义(P<0．05,P<0．01)。结论:痰热清注射液治疗CAP效果良好,退热作用显著,并有清除氧自由基的作用。

Objective： To observe the curative effect of Tanreqing Injection （TI） fbr community acquired pneumonia （CAP）. Methods： 100 cases were allocated to treatment group （50 cases） and control group （50 cases） randomly, and were treated by routine western medicine （WM） and added with TI for treatment group. The clinical curative effect of both groups, the count of WBC before and after treatment, the parameters of total serum superoxide dismutase （T-DOD） and serum malondialdehyde （MDA） were observed, Results： The cured and markedly effective rate was 88% and 62% in treutment group and control group respectively （ P 〈 0. 01 ）. In treatment group, the Ist day after treatment showed that the body tempcrature was markedly decreased and basic normal in the 2nd day and completely nonnal in the 3rd day, the comparison with control group showed very markedly significant difference （P 〈 0.01 ）. In treatment group, the 1st day after treatment showed that the count of WBC was markedly decreased and normal in the 2nd day , comparison with before treatment showed very markedly significant difference （ P 〈 0.01 ）; the comparison of same period with control group showed very markedly significant difference （ P 〈 0.01 ）. After treatment, the T - SOD and MDA were in,proved in both groups, comparison with before treatment showed markedly or very markedly significant difference （ P 〈 0.05, P 〈 0.01 ）; afier treatment, the comparison of treatment group and control group showed markedly or very markedly significant difference （ P 〈 0.05, P 〈 0.01）. Conclusion： TI possesses good effect for CAP and marked effect for abatement of fever and clearance of oxygen free radical.