期刊文献+

新型肾素阻滞药——阿利吉仑

下载PDF
导出
摘要 新一代非肽类肾素阻滞药阿利吉仑,口服后迅速吸收,药效持续时间长,与内源性肾素竞争性地紧密结合,发挥降血压等作用,且不良反应少,治疗依从性相对较好。
出处 《医药导报》 CAS 2006年第3期255-256,共2页 Herald of Medicine
  • 相关文献

参考文献10

  • 1Dzau V J.Tissue angiotensin and pathobiology of vascular disease,aunifying hypothesis[J].Hypertension,2001,37(4):1047-1052.
  • 2Dahlof B,Devereux R B,Kjeldsen,et al.Cardiovascular morbidity and mortality in the losartan intervention for endpoint reduction in hypertention study (LIFE):a randomized trial against atenolol[J].Lancet,2002,359(9311):995-1003.
  • 3Vanden Meiracker A H,Admiraal P J,Derkx F H,et al.Comparison of blood pressure and angiotensin responses to the renin inhibitor RO42-5892 and the angiotension-converting enzyme inhibitor enalapril in essential hypertension[J].Hypertens,1993,11(8):831-838.
  • 4Fisher N D,Hollenberg N K.Is there a future for renin inhibitors?[J].Exp Opin Invest Drugs,2001,10(3):417-426.
  • 5Wood J,Maibaum J,Rahuel J,et al.Structure-based design of ali-skiren,a novel orally effective renin inhibitor[J].Bio Biophys Res Commu,2003,308(4):698-705.
  • 6Nussberger J,Wuerzner G,Jensen C,et al.Angiotensin Ⅱ suppres-sion in humans by the orally active renin inhibitor aliskiren(SPP100):comparison with enalapril[J].Hypertension,2002,4(4):269-270.
  • 7Stanton A.Therapeutic potential of rennin inhibitors in the mana-gement of cardiovascular disorders[J].Am J Cardiovasc Drugs,2003,3(6):389-394.
  • 8Stanton A,Jensen C,Nussberger J,et al.Blood pressure lowering in essential hypertension with an oral renin inhibitor,Aliskiren[J].Hypertension,2003,42(6):1137-1143.
  • 9Dieterle W,Corynen S,Mann J.Effect of the oral inhibitor aliskiren on the pharmacokinetics and pharmacodynamics of a single dose of warfarin in healthy subjects[J].Br J Clin Pharma,2004,58(4):433-436.
  • 10Allikmets K.Aliskiren(Speedel)[J].Curr Opin Investig Drugs,2002,3(10):1479-1482.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部