糖尿病肾病重度浮肿患者短时低效每日透析的疗效分析

Study on Short-term Slow Low Efficient Daily Dialysis in Cases of Diabetic Nephropathy With Severe Edema

目的：研究短时低效每日血液透析（STSLEDD）在糖尿病肾病（DN）重度浮肿患者的临床应用情况，为改善糖尿病患者的临床症状提供一个新方法。方法：选择DN伴重度浮肿患者31例，随即分为两组（A、B）。A组采用STSLEDD加DN常规药物治疗；B组单纯DN常规药物治疗。A组每日行血液透析9h，连续3～5d，同时观察两组患者尿蛋白、血浆蛋白、肾功能、浮肿等变化情况。结果：A、B两组治疗后尿蛋白减少、血浆蛋白上升、肾功能均得到不同程度的改善。A组所有患者浮肿均完全消退。A组较B组临床症状改善更明显（P〈0．05）。结论：STSLEDD对DN合并重度浮肿患者有明显疗效。

Objective. To study the clinical application of short-term, slow low efficient daily dialysis （STSLEDD） in cases of diabetic nepbxopathy with severe edema, Methods： 31cases were divided into two groups randomly , Group A used STSLEDD and conventional drugs, group B received drugs only. Group A was treated by dialysis 9 hours daily, continued for 3 to 5 days. The urinary protein, plasma proteins, renal functions were observed in group A and B. Results： The urinary protein was reduced, the plasma proteins increased, renal functions improved in both group A and B. The improvement in group A was much evident than in group B（p〈0. 05）. Conclusion： STSLEDD has remarkable effect on diabetic nephropathy with severe edema.