慢性重型病毒性肝炎并自发性细菌性腹膜炎的临床分析

A Clinical Analysis on Chronic Severe Viral Hepatitis Complicated With Spontaneous Bacterial Peritonitis

通过对28例合并自发性细菌性腹膜炎的慢性重型病毒性肝炎患者和32例不合并自发性腹膜炎的慢性重型病毒性肝炎患者的临床资料进行分析,发现慢性重型病毒性肝炎患者合并自发性腹膜炎者临床表现不典型,出现口腔感染及肺部感染比例高于无腹膜炎的患者(P<0.01);合并自发性腹膜炎患者的慢重肝患者肝性脑病、上消化道出血、肝肾综合征等并发症的发生率显著高于不合并自发性腹膜炎的慢重肝患者。提示慢性重型病毒性肝炎并自发性细菌性腹膜炎起病较隐匿,应及早诊断并治疗。

Objective Through review the clinical data of 28 patients with chronic severe viral hepatitis complicated with spontaneous bacterial peritonitis and 32 chronic severe viral hepatitis patients not complicated with spontaneous bacterial peritonitis, the results showed that the clinical manifestation of chronic severe viral hepatitis patients complicated with spontaneous bacterial peritonitis is not typical. There were high incidences of oral and pulmonary infections among the patients complicated with spontaneous bacterial peritonitis as compared with those without spontaneous peritonitis （P〈 0.01）. The occurrences of hepatoencephalopathy, upper gastrointestinal bleeding, and hepatorenal syndrome among those who complicated with spontaneous bacterial peritonitis were higher too. These results suggested that spontaneous bacterial peritonitis in patients with chronic severe viral hepatitis occurs insidiously, which requires early detection, diagnosis and treatment.