美丽红豆杉种子化学成分的研究(Ⅳ)

A novel lupane triterpene from seeds of Ziziphus jujuba var.spinosa

目的研究美丽红豆杉T axusm a irei种子的化学成分。方法采用柱色谱、制备TLC、制备HPLC法和光谱法分离鉴定化学成分。结果从美丽红豆杉种子中分离得到6个紫杉烷类化合物,鉴定为13-αacety lbrev ifo lio l(Ⅰ)、taxayun tin E(Ⅱ)、acety ltax in ine B(Ⅲ)、5-ep i-canadensene(Ⅳ)、2,α9,α10,β13-tetraacetoxy-20-c innam oy loxy-taxa-4(5),11(12)-d iene(Ⅴ)、taxach itrienes B(Ⅵ)。结论它们均为首次从该植物种子中获得。

Objective To study the chemical constituents in the seeds of Taxus mairei. Methods Column chromatography preparative TLC, preparative HPLC, and spectroscopic analyses were used to isolate and elucidate the chemical constituets in the plant. Results Six taxane diterpenoids were isolated from the seeds of T. mairei and identified as 13α-acetylbrevifoliol （ Ⅰ）, taxayuntin E （Ⅱ）, acetyltaxinine B （ Ⅲ）, 5-epi-canadensene （ Ⅳ）, 2α, 9α, 10β, 13-tetraacetoxy-20-cinnamoyloxy-taxa-4（5）, 11 （12）-diene （Ⅴ）, taxachitrienes B （ Ⅵ）. Conclusion All the compounds are obtained from the seeds of this plant for the first time.