严重多发伤后C-反应蛋白和血糖的变化及临床意义

Changes and clinical significance of C-reactive protein and blood glucose following severe multiple injuries.

目的探讨严重多发伤患者血糖和C-反应蛋白(CRP)的变化及临床意义。方法检测67例严重多发伤患者入院后第1、3、7天空腹血糖和CRP水平,并与同期68例轻度多发伤患者(对照组)进行比较。结果重创组第1、3、7天的CRP和血糖水平均明显高于对照组(均为P<0.05);第1天创伤严重度评分与相应时相血糖水平正相关(P<0.05),与相应时相CRP水平正相关(P<0.05)。结论严重多发伤后血糖和CRP水平的高低与创伤严重度呈正相关,持续增高提示预后不佳。

Objective To study the changes and clinical significance of C-reactive protein （CRP） and blood glucose following severe multiple injuries. Methods The levels of fasting blood glucose and CRP at the 1,3 and 7th day after admission were measured in 67 cases with severe multiple injury and compared with that of 68 cases with slight multiple injury at the same period. Results The levels of fasting blood glucose and CRP at the 1,3 and 7th day after admission were significantly higher in cases of server multiple injury than those of control group （ P 〈 0.05）. The injury severity scoring at the 1 st day was positively correlated with blood glucose level and CRP level at the same time （ P 〈 0.05 for each）. Conclusion The levels of fasting blood glucose and CRP following severe multiple injury are positively correlated with the severity of injury,and their continuous increase suggests the poorer prognosis.