肝硬化患者高生长激素血症的临床意义

CLINICAL SIGNIFICANCE OF HIGH SERUM GROWTH HORMONE LEVEL IN PATIENTS WITH CIRRHOSIS

本文报告50例肝硬化患者空腹血清生长激素检测结果,52％患者的生长激素水平升高;代偿期均值为3.47±2.64μg/L,失代偿期均值为14.33±13.17μg/L,后者明显高于前者(t=3.25,P<0.01)。本文检测结果表明肝硬化患者血清生长激素水平升高与肝病严重程度成正相关。检测肝硬化患者的血清生长激素水平,有助估价肝功能状况,指导临床治疗。对伴有高生长激素血症患者尚须注意糖代谢紊乱。

The serum growth hormone level (SGHL) were detected for 50 cases of cirrhotic patients. The results showed that 52％ out of the our cases SGHL were elevated. The mean value of the SGHL in case of compensatory stage are 3.47±2.64μg/L significant lower than that of the decompensatory stage 14.33±13.17μg/L. The data, explained that SGHL positively correlated with degree of severity of liver cirrhosis. The authors belive that to detected for SGHL in patient with liver cirrhosis be much helps to evaluation of the liver function. In addition, it was suggested that in case of patients with higher SGHL should pay attention to glucose be evident of metabolic disturbance.