摘要
血管内皮是指一种单层内皮细胞，覆盖在血管床内腔表面，具有机械和代谢功能，并将血管壁和循环以及血液中的有形成份分隔开来。大量的研究证据表明，内皮功能障碍作为一种综合征，不仅与心血管事件密切相关，而且可以引起全身性症状，具有很高的死亡率和病死率。本文综述近年来有关内皮功能研究的一些最新进展，同时分析其在心血管事件危险评估中的预测价值。
出处
《中国医药导刊》
2006年第1期18-20,共3页
Chinese Journal of Medicinal Guide
参考文献22
-
1Herrmann J,Lerman LO,Rodriguez-Porcel M,et al.Coronary vasa vasorum neovascularization precedes epicardial endothelial dysfunction in experimental hypercholesterolemia.Cardiovasc Res,2001;51:762 ～ 766
-
2Rafii S,Lyden D.Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration.Nat Med,2003;9:702 ～ 712
-
3Targonski PV,Bonetti PO,Pumper GM,et al.Coronary endothelial dysfunction is assotiated with an increased risk of cerebrovascular events.Circulation,2003;107:2805 ～ 2809
-
4Asselbergs FW,Monnink SH,Jessurun GA,etal.Assessing the prognostic value of coronary endothelial function in patients referred for a first coronary angiogram.Am J Cardiol,2004;94:1063 ～ 1067
-
5Suwaidi JA,Hamasaki S,Higano ST,et al.Long-term follow-up of patients with mild coronary heart disease and endothelial dysfunction.Circulation,2000;101:948 ～ 954
-
6Ganz P,Vita JA.Testing endothelial vasomotor function:nitric oxide,a multipotent molecule.Circulation,2003;108:2049 ～ 2053
-
7Juonala M,Viikari JS,Laitinen T,et al.Interrelations between brachial endothelial function and carotid intima-media thickness in young adults:the cardiovascular risk in young Finns study.Circulation,2004;110:2918 ～ 2923
-
8Bonetti PO,Lerman A.Endothelial dysfunction:a marker of atherosclerotic risk.Arterioscler Thromb Vasc Biol,2003;23:168 ～ 175
-
9Wagner D,Saffaripour S,Bonfanti R,et al.Induction of specific storage organelles by von Willebrand factor propolypeptide.Cell,1991;64:403 ～ 413
-
10Naghavi M,Libby P,Falk E,et al.From vulnerable plaque to vulnerable patient:a call for new definations and risk assessment strategies,Ⅰ.Circulation,2003;108:1644 ～ 1672
同被引文献24
-
1郭建友,霍海如,姜廷良.内皮细胞功能及其异质性研究的进展[J].中国临床药理学与治疗学,2005,10(10):1081-1085. 被引量：9
-
2Galley HF, Webster NB. Physioligy of endothelium [cardiovascular disease in anaesthesia and critical care]. Br J Anaeth, 2004, 93:105-113.
-
3Choi K, Kennedy M, Kazarov A, et al. A common precursor for hematopoietic and endothelial cells. Development, 1998, 125: 725 -732.
-
4Gallagher G, Sumpio BE. Vascular endothelial cells// Sumpio BE, Sidawy AS. Basic Science of Vascular Disease. Mt. Kisco: Futura Publishing Co, 1997, 151-186.
-
5Galley HF, Blaylock MG, Dubbels AM, et al. Variability in Eselectin expression, mRNA levels and sE-selectin release between endothelial cell lines and primary endothelial cells. Cell Biol Int, 2000, 24: 91-99.
-
6Wemer N, Nickening G. Influence of cardiovascular risk factors on endothelial progenitor cells: limitations for therapy? Arterioscler Thromb Vase Biol, 2006, 26: 257-266.
-
7Schwartz SM, Benditt EP. Clustering of replicating cells in aortic endothelium. Proc Natl Acad Sci U S A, 1976, 73: 651-653.
-
8Crosby JR, Kaminski WE, Schatteman G, et al. Endothelial cells of hematopoietic origin make a significant contribution to adult blood vessel formation. Circ Res, 2000, 87 : 728-730.
-
9Wemer N, Priller J, Laufs U, et al. Bone marrow-derived progenitor cells modulate vascular reendothelialization and neointimal formation: effect of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibition. Arterioscler Thromb Vasc Biol, 2002, 22 : 1567- 1572.
-
10Werner N, Junk S, Laufs U, et al. Intravenous transfusion of endothelial progenitor cells reduces neointima formation after vascular injury. Circ Res, 2003, 93: e17-e24.
-
1梁雅梅,郭贤利.内皮功能障碍与缺血性心脏病[J].延安大学学报（医学科学版）,2007,5(3):6-7. 被引量：1
-
2王晓峰,董海兴,秦永文.多巴酚丁胺、心得安在动脉单层内皮细胞上对脂类代谢的影响[J].心血管康复医学杂志,1999,8(2):18-20.
-
3线利波,曹凤华,贾程之.不稳定型心绞痛血液流变性改变[J].中国微循环,2003,7(4):226-226.
-
4曾华君.住院精神障碍患者自杀自伤危险评估及护理干预[J].医学美学美容（中旬刊）,2014,23(12):508-508.
-
5陈九如.肝脏疾病影像学诊断与鉴别诊断(Ⅱ) 肝脏常见疾病的影像学诊断与鉴别诊断[J].国际医学放射学杂志,2010,33(2):158-167. 被引量：5
-
6王劲,张荷,洪林,许利民.全血有形成份减少与感染关系的临床分析[J].第三军医大学学报,2002,24(1):61-61.
-
7张娟安,王长征,吴晶晶,胡友明.显微摄片在尿液形态学教学中的应用研究[J].重庆医学,2011,40(20):2033-2034.
-
8樊勇,白德成.高血黏度大鼠血液有形成份及血液流变性的动态观察[J].中国微循环,2005,9(2):104-107. 被引量：6
-
9林金秤,汤显湖.免疫吸附在治疗重症狼疮性肾炎的临床研究[J].医学信息,2012,25(10):109-109. 被引量：1
-
10张鹏,汪南平.脂联素与心血管疾病[J].生理科学进展,2007,38(2):149-152. 被引量：9
