期刊文献+

SELDI-TOF-MS技术在妇科恶性肿瘤早期诊断中的应用 被引量:1

下载PDF
导出
摘要 表面增强激光解吸电离飞行时间质谱(SELDI-TOF-MS)是近年出现的蛋白质研究新技术。其综合了蛋白芯片和质谱技术的优点,可通过蛋白表达图谱模式快速筛选肿瘤标志物,进行肿瘤的早期诊断。卵巢癌、宫颈癌及子宫内膜癌等研究资料显示,其敏感性和特异性均优于传统的肿瘤诊断方法,在妇科肿瘤早期诊断方面有巨大应用前景。
作者 张辉 孔北华
出处 《国外医学(妇产科学分册)》 2006年第1期36-39,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
  • 相关文献

参考文献20

  • 1Saslow D,Runowicz CD,Solomon D,et al.American Cancer Society Guideline for the early detection of cervical neoplasia and cancer.CA Cancer J Clin,2002,52 (6):342-362.
  • 2Tewari KS,Kyshtoobayeva AS,Mehta RS,et al.Biomarker conservation in primary and metastatic epithelial ovarian cancer.Gynecol Oncol,2000,78(2):130-136.
  • 3Menon U,Jacobs I.Recent developments in ovarian cancer screening.Curr Opin Obstet Gynecol,2000,12(1):39-42.
  • 4Cohen LS,Escobar PF,Scharm C,et al.Three dimensional power Doppler ultrasound imp roves the diagnostic accuracy for ovarian cancer prediction.Gynecol Oncol,2001,82(1):40- 48.
  • 5Smith RA,Cokkinides V,Eyre HJ.American cancer society Guidelines for the early detection of cancer.CA Cancer J Clin,2003,53(1):27-43.
  • 6Merchant M,Weinberger SR.Recent advancements in surface enhanced laser desorption/i onization time of flight mass spectrometry.Electrophoresis,2000,21 (6):1164 - 1177.
  • 7Li J,Zhang Z,Rosenzweig J,et al.Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer.Clin Chem,2002,48(8):1296-1304.
  • 8Cazares LH,Adam BL,Ward MD,et al.Normal,benign,preneoplastic and malignant prostate cells have distinct protein expression profiles resolved by surface enhanced laser desorption/ ionization mass spectrometry.Clin Cancer Res,2002,8(8):2541-2552.
  • 9Vlahou A,Schellhammer PF,Mendrinos S,et al.Development of a novel proteomic approach for the detection of transitional cell carcinoma of the bladder in urine.Am J Pathol,2001,158(4):1491-1502.
  • 10Petricoin EF,Ardekani AM,Hitt BA,et al.Use of proteomic patterns in serum to identify ovarian cancer.Lancet,2002,359(9306):572-577.

同被引文献24

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部