摘要
目的确定牛蒡子口腔崩解片的处方。方法采用正交设计法选择牛蒡子口腔崩解片的处方。结果确定牛蒡子口腔崩解片处方中主要的成分配比为:交联聚乙烯吡咯烷酮8%,微晶纤维素25%,α-乳糖25%。结论确定了牛蒡子口腔崩解片的处方,但是此片剂口感一般,须进一步研究。
OBJECTIVE To determine the formulation of the rapidly disintegrating oral tablet of Arctium lappa L. METHODS Formulae of the rapidly disintegrating oral tablet were selected with a method of orthogonal design. RESULTS The percentage of the major ingredients in the formulation of the tablets was determined;PVPP8 % ,MCC 25 % ,and α-lactose 25 %. CONCLUSION The formulation of the oral tablets was optimized. Since the taste of the medication was not good enough,Studies on palatability should be carried out in the nest step.
出处
《海峡药学》
2006年第1期22-24,共3页
Strait Pharmaceutical Journal
关键词
口腔崩解片
处方
正变设计
Rapidly disintegrating oral tablet
Determine
Formulation
