新一代动物无创血压测定仪的研制及性能检验

EXPLOITATION OF A NEW NONINVASIVE ANIMAL'S BLOOD PRESSURE MEASURING APPARATUS AND ITS FUNCTION CHARACTERIZATION

目的:研制新一代“动物无创血压测定仪”。方法:本研究利用与人血压测定相似的原理,以自行开发、拥有自主知识产权的专用软件克服了动物舒张压的测定点较难精确标定的困难,成功研制出新一代“动物无创血压测定仪”。并与经典的动物有创血压测定法行同步比较。结果:在正常血压、高血压、低血压等不同情况下,两法测值极为相近,相关系数皆大于0.9。结论:本研制的新一代“动物无创血压测定仪”可作为家兔、大鼠血压无创测定的可靠方法。

Aim： To produce a new, noninvasive, animal＇ s blood pressure measuring apparatus. Methods： By applying the principle similar with the measurement of human blood pressure, we developed a software which knowledge property owned by this research group and solved the problems of exactly demarcating the measuring spot of diastolic pressure. The blood pressure of rabbits was measured by the novel noninvasive animal＇s blood pressure measuring apparatus and the classic surgical catheterizing method simultaneously. Results： The novel noninvasive animal＇ s blood pressure measuring apparatus was successfully set up. The measured blood pressures by this apparatus are very similar（ r 〉0.9） with the values obtained from the classic, surgical eatheterizing method, no matter the blood pressures are normal, high or low. Conclusion： Our new apparatus can be a reliable method for noninvasive measurement of the blood pressure of rabbits and rats.